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1.CRISPR tech selectively shreds cancer cells, including "undruggable" cancers (innovativegenomics.org)
431 points by gmays 4 hours ago | hide | 110 comments
2.I Am Not a Reverse Centaur (miguelgrinberg.com)
130 points by ibobev 2 hours ago | hide | 88 comments
3.Kagi Magic (kagi.com)
15 points by amirmasoudabdol 12 minutes ago | hide | discuss
4.How to setup a local coding agent on macOS (ikyle.me)
95 points by kkm 2 hours ago | hide | 33 comments
5.Malware developers added nuclear and biological weapons text to to their spyware (twitter.com/jsrailton)
146 points by marc__1 4 hours ago | hide | 91 comments
6.Pirates, a naval warfare game inspired by Sid Meier's Pirates (piwodlaiwo.github.io)
75 points by iweczek 2 hours ago | hide | 30 comments
7.Looking Forward to Postgres 19: It's About Time (pgedge.com)
81 points by xngbuilds 3 hours ago | hide | 22 comments
8.A PDF that changes based on how its read (sgaud.com)
76 points by SarthakGaud 3 hours ago | hide | 39 comments
9.Slightly reducing the sloppiness of AI generated front end (envs.net)
127 points by FergusArgyll 5 hours ago | hide | 81 comments
10.Law Enforcement's "Warrior" Problem (2015) (harvardlawreview.org)
42 points by bookofjoe 2 hours ago | hide | 36 comments
11.Launch HN: BitBoard (YC P25) – Analytics Workspace for Agents (bitboard.work)
18 points by arcb 3 hours ago | hide | 8 comments
12.A dumpster arrived behind my university's library (yalereview.org)
128 points by mooreds 5 hours ago | hide | 104 comments
13.Where Did Earth Get Its Oceans? Maybe It Made Them Itself (quantamagazine.org)
72 points by ibobev 4 hours ago | hide | 45 comments
14.There Is Life Before Main in Rust (grack.com)
40 points by mmastrac 3 hours ago | hide | 12 comments
15.AI agent bankrupted their operator while trying to scan DN42 (lantian.pub)
1333 points by xiaoyu2006 15 hours ago | hide | 481 comments
16.Introduction to UEFI HTTP(s) Boot with QEMU/OVMF (yadutaf.fr)
43 points by jtlebigot 5 hours ago | hide | 12 comments
17.Cosmodial Sky Atlas (killedbyapixel.github.io)
13 points by memalign 1 hour ago | hide | 1 comment
18.Maxproof (arxiv.org)
116 points by ilreb 7 hours ago | hide | 9 comments
19.A Call to Action: Stop the FCC's KYC Regime (lopp.net)
276 points by FergusArgyll 5 hours ago | hide | 179 comments
20.Hazel (YC W24) Is Hiring a Full Stack Engineer (ycombinator.com)
6 hours ago | hide
21.WASI 0.3 (bytecodealliance.org)
201 points by mavdol04 6 hours ago | hide | 82 comments
22.If you are asking for human attention, demonstrate human effort (tombedor.dev)
1403 points by jjfoooo4 20 hours ago | hide | 441 comments
23.Show HN: StackScope – I crawled over 40k indie launches to see what they ship (stackscope.dev)
29 points by datafreak_ 4 hours ago | hide | 8 comments
24."Don't You Just Upload It to ChatGPT?" (correresmidestino.com)
109 points by speckx 2 hours ago | hide | 105 comments
25.New privacy frontier: Europe eyes crackdown on smart glasses (politico.com)
59 points by 1vuio0pswjnm7 3 hours ago | hide | 42 comments
26.How we made hit video game Prince of Persia (theguardian.com)
252 points by msephton 17 hours ago | hide | 103 comments
27.Encrypted Spaces An architecture for collaborative applications (encryptedspaces.org)
49 points by _____k 7 hours ago | hide | 5 comments
28.Kimi K2.7-Code: open-source coding model with better token efficiency (huggingface.co)
353 points by nekofneko 9 hours ago | hide | 192 comments
29.A jacket that harvests drinking water from the air (utexas.edu)
145 points by ilreb 20 hours ago | hide | 92 comments
30.Show HN: Script to bulk delete Claude chats from the web UI (github.com/matteoleonesi)
44 points by ML0037 4 hours ago | hide | 16 comments

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