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1.CRISPR tech selectively shreds cancer cells, including "undruggable" cancers (innovativegenomics.org)
342 points by gmays 3 hours ago | hide | 89 comments
2.I Am Not a Reverse Centaur (miguelgrinberg.com)
69 points by ibobev 1 hour ago | hide | 25 comments
3.How to Setup a Local Coding Agent on macOS (ikyle.me)
41 points by kkm 1 hour ago | hide | 9 comments
4.Pirates, a naval warfare game inspired by Sid Meier's Pirates (piwodlaiwo.github.io)
41 points by iweczek 1 hour ago | hide | 17 comments
5.A PDF that changes based on how its read (sgaud.com)
66 points by SarthakGaud 2 hours ago | hide | 30 comments
6.Slightly reducing the sloppiness of AI generated front end (envs.net)
115 points by FergusArgyll 4 hours ago | hide | 73 comments
7.Looking Forward to Postgres 19: It's About Time (pgedge.com)
53 points by xngbuilds 2 hours ago | hide | 17 comments
8.Malware developers added nuclear and biological weapons text to to their spyware (twitter.com/jsrailton)
103 points by marc__1 3 hours ago | hide | 79 comments
9.A dumpster arrived behind my university's library (yalereview.org)
112 points by mooreds 4 hours ago | hide | 86 comments
10.Tesla Full Self Driving uses bicycle lane in official Denmark approval video (politiken.dk)
77 points by Veserv 1 hour ago | hide | 20 comments
11.Where Did Earth Get Its Oceans? Maybe It Made Them Itself (quantamagazine.org)
64 points by ibobev 3 hours ago | hide | 41 comments
12.Launch HN: BitBoard (YC P25) – Analytics Workspace for Agents (bitboard.work)
15 points by arcb 1 hour ago | hide | 4 comments
13.There Is Life Before Main in Rust (grack.com)
29 points by mmastrac 2 hours ago | hide | 8 comments
14.Cosmodial Sky Atlas (killedbyapixel.github.io)
6 points by memalign 38 minutes ago | hide | 1 comment
15.AI agent bankrupted their operator while trying to scan DN42 (lantian.pub)
1299 points by xiaoyu2006 14 hours ago | hide | 473 comments
16.Introduction to UEFI HTTP(s) Boot with QEMU/OVMF (yadutaf.fr)
33 points by jtlebigot 4 hours ago | hide | 8 comments
17.Hazel (YC W24) Is Hiring a Full Stack Engineer (ycombinator.com)
5 hours ago | hide
18.Keygen.music (keygen.music)
97 points by soupspaces 3 hours ago | hide | 58 comments
19.A Call to Action: Stop the FCC's KYC Regime (lopp.net)
266 points by FergusArgyll 4 hours ago | hide | 170 comments
20.Maxproof (arxiv.org)
108 points by ilreb 6 hours ago | hide | 8 comments
21.Law Enforcement's "Warrior" Problem (2015) (harvardlawreview.org)
22 points by bookofjoe 1 hour ago | hide | 13 comments
22.WASI 0.3 (bytecodealliance.org)
191 points by mavdol04 5 hours ago | hide | 76 comments
23."Don't You Just Upload It to ChatGPT?" (correresmidestino.com)
77 points by speckx 1 hour ago | hide | 71 comments
24.I Won't Buy You a Coffee (hakkerman.eu)
16 points by speckx 21 minutes ago | hide | 12 comments
25.If you are asking for human attention, demonstrate human effort (tombedor.dev)
1378 points by jjfoooo4 19 hours ago | hide | 439 comments
26.New privacy frontier: Europe eyes crackdown on smart glasses (politico.com)
43 points by 1vuio0pswjnm7 2 hours ago | hide | 26 comments
27.Encrypted Spaces An architecture for collaborative applications (encryptedspaces.org)
44 points by _____k 6 hours ago | hide | 5 comments
28.Show HN: StackScope – I crawled over 40k indie launches to see what they ship (stackscope.dev)
24 points by datafreak_ 3 hours ago | hide | 7 comments
29.How we made hit video game Prince of Persia (theguardian.com)
246 points by msephton 16 hours ago | hide | 92 comments
30.Show HN: Script to bulk delete Claude chats from the web UI (github.com/matteoleonesi)
41 points by ML0037 3 hours ago | hide | 12 comments

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