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1. Scientists glue two proteins together, driving cancer cells to self-destruct (stanford.edu)
336 points by Jerry2 9 hours ago | hide | 83 comments
2. An embarrassingly simple approach to recover unlearned knowledge for LLMs (arxiv.org)
120 points by PaulHoule 7 hours ago | hide | 33 comments
3. Project Sid: Many-agent simulations toward AI civilization (github.com/altera-al)
311 points by talms 14 hours ago | hide | 94 comments
4. Hertz-dev, the first open-source base model for conversational audio (si.inc)
143 points by mnk47 10 hours ago | hide | 29 comments
5. I've had a change of heart regarding employee metrics (rachelbythebay.com)
227 points by zdw 4 hours ago | hide | 117 comments
6. Touchscreens are out, and tactile controls are back (ieee.org)
952 points by pseudolus 19 hours ago | hide | 657 comments
7. A Hamiltonian Circuit for Rubik's Cube (cubing.net)
65 points by jcalx 11 hours ago | hide | 17 comments
8. Cannot Measure Productivity (martinfowler.com)
22 points by aard 1 hour ago | hide | 2 comments
9. pg_flo – Stream, transform, and re-route PostgreSQL data in real-time (pgflo.io)
171 points by shayonj 16 hours ago | hide | 27 comments
10. Interview gone wrong (ashu1461.com)
86 points by ashu1461 8 hours ago | hide | 118 comments
11. Programming languages that blew my mind (2023) (yoric.github.io)
242 points by todsacerdoti 19 hours ago | hide | 130 comments
12. PacCam: Pac-Man controlled with your face (eieio.games)
37 points by bblcla 13 hours ago | hide | 6 comments
13. Open-source wheeled biped robot (github.com/upkie)
15 points by surmoi 5 hours ago | hide | 4 comments
14. gptel: a simple LLM client for Emacs (github.com/karthink)
123 points by michaelsbradley 16 hours ago | hide | 27 comments
15. GJS: Node.js Like Runtime for Gnome (gjs.guide)
27 points by AbuAssar 11 hours ago | hide | 4 comments
16. The Submerged Nabataean Temple in Puteoli at Pozzuoli, Italy (cambridge.org)
43 points by aguaviva 15 hours ago | hide | 12 comments
17. Top discoveries about ancient people from DNA in 2023 (johnhawks.net)
61 points by softwaredoug 17 hours ago | hide | 3 comments
18. Hermes 3 – Nous Research (nousresearch.com)
23 points by jasim 13 hours ago | hide | 1 comment
19. Show HN: Tinder, but to Decide What to Eat (whatdinner.com)
158 points by kiru_io 13 hours ago | hide | 141 comments
20. Ritonavir Form III: A Coincidental Concurrent Discovery (acs.org)
8 points by f1shy 4 hours ago | hide | 1 comment
21. Programming NetBIOS on OS/2 (os2museum.com)
51 points by userbinator 20 hours ago | hide | discuss
22. Missing open-source contributor presents a dilemma when accepting their PR (bettersoftware.uk)
66 points by FrankRay78 17 hours ago | hide | 44 comments
23. Venvstacks: Virtual Environment Stacks for Python (lmstudio.ai)
102 points by ingve 1 day ago | hide | 45 comments
24. Ask HN: What would you preserve if the internet were to go down tomorrow?
157 points by gooob 1 day ago | hide | 192 comments
25. Unix core utilities implemented in Haskell (github.com/gandalf-)
222 points by ocean_moist 1 day ago | hide | 82 comments
26. A React Renderer for Gnome JavaScript (github.com/react-gjs)
129 points by bcye 21 hours ago | hide | 62 comments
27. Show HN: Replacicon – Create and customize app icons on macOS (replacicon.app)
32 points by simonp9 13 hours ago | hide | 13 comments
28. GoGoGrandparent (YC S16) Is Hiring Back End and Full-Stack Engineers
16 hours ago | hide
29. USB Insight Hub (crowdsupply.com)
10 points by ofrzeta 4 hours ago | hide | 2 comments
30. Why systemd is a problem for embedded Linux (kevinboone.me)
171 points by synergy20 12 hours ago | hide | 177 comments

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