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1. AlphaFold: a solution to a 50-year-old grand challenge in biology (deepmind.com)
1353 points by felixr 5 hours ago | hide | 388 comments
2. BBC Basic Editor (bbcmic.ro)
117 points by mnem 2 hours ago | hide | 18 comments
3. The Covid Science Wars (scientificamerican.com)
16 points by johntfella 19 minutes ago | hide | 3 comments
4. Why is Apple's M1 chip so fast? (erik-engheim.medium.com)
143 points by socialdemocrat 1 hour ago | hide | 158 comments
5. I Made a Self-Quoting Tweet (oisinmoran.com)
73 points by OisinMoran 2 hours ago | hide | 10 comments
6. A free-as-in-freedom re-implementation of Google’s Android user space (microg.org)
599 points by doener 9 hours ago | hide | 152 comments
7. Running a full desktop environment on an Amazon Kindle (nns.ee)
27 points by slondr 1 hour ago | hide | 5 comments
8. AlphaFold2 dominates CASP14 protein structure challenge (predictioncenter.org)
196 points by momeara 7 hours ago | hide | 37 comments
9. E Foundation – deGoogled unGoogled smartphone OS and online services (e.foundation)
275 points by lelf 8 hours ago | hide | 96 comments
10. The new 'gold rush' for green lithium (bbc.com)
47 points by clouddrover 3 hours ago | hide | 9 comments
11. Objects in Functional Languages (infinitenegativeutility.com)
10 points by todsacerdoti 45 minutes ago | hide | discuss
12. The Sound So Loud That It Circled the Earth Four Times (nautil.us)
35 points by singhkays 2 hours ago | hide | 12 comments
13. The Gernsback Continuum by William Gibson (1981) (archive.org)
60 points by pmoriarty 4 hours ago | hide | 30 comments
14. YC runs Work at a Startup to help you find jobs at over 700 YC-vetted startups (workatastartup.com)
3 hours ago | hide
15. Email Lessons from Napoleon (thesweetsetup.com)
4 points by hecubus 18 minutes ago | hide | 2 comments
16. Apple Create ML: Creating an Image Classifier Model (developer.apple.com)
197 points by tosh 7 hours ago | hide | 48 comments
17. Adopt your elePHPant now, the only original PHP elephant (elephpant.com)
16 points by waskip 1 hour ago | hide | 4 comments
18. Post PC (asymco.com)
5 points by ingve 24 minutes ago | hide | discuss
19. No one who got Moderna's vaccine in trial developed severe Covid-19 (sciencemag.org)
293 points by jakozaur 6 hours ago | hide | 290 comments
20. Guybrush Fact vs. Fiction (grumpygamer.com)
118 points by pmarin 7 hours ago | hide | 39 comments
21. Writing Rust the Elixir Way (kutt.it)
194 points by bkolobara 8 hours ago | hide | 93 comments
22. Chess tactics explained (chesstactics.org)
484 points by kensai 14 hours ago | hide | 213 comments
23. Error Handling Is Hard (fpcomplete.com)
37 points by phonebucket 5 hours ago | hide | 56 comments
24. FCC Chairman Ajit Pai will step down on January 20 (cnbc.com)
143 points by dredmorbius 3 hours ago | hide | 49 comments
25. On Casuistry (philosophynow.org)
3 points by smollett 18 minutes ago | hide | discuss
26. Tech’s flight from San Francisco is a relief to some advocates (cnbc.com)
50 points by harambae 3 hours ago | hide | 99 comments
27. What changes when you work outside an office? (vinko.substack.com)
34 points by koide 4 hours ago | hide | 36 comments
28. H. G. Wells reviews "Metropolis" (1927) (tsudao.com)
3 points by pmoriarty 24 minutes ago | hide | discuss
29. Legal Concepts for Founders (clerky.com)
148 points by sarathyweb 9 hours ago | hide | 23 comments
30. Show HN: Keenforms – Form Builder with No-Code Rules Engine (keenforms.com)
30 points by padseeker 4 hours ago | hide | 8 comments

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