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1. AlphaFold: a solution to a 50-year-old grand challenge in biology (deepmind.com)
1204 points by felixr 4 hours ago | hide | 349 comments
2. Why is Apple's M1 chip so fast? (erik-engheim.medium.com)
28 points by socialdemocrat 22 minutes ago | hide | 14 comments
3. BBC Basic Editor (bbcmic.ro)
85 points by mnem 1 hour ago | hide | 15 comments
4. A free-as-in-freedom re-implementation of Google’s Android user space (microg.org)
572 points by doener 8 hours ago | hide | 140 comments
5. E Foundation – deGoogled unGoogled smartphone OS and online services (e.foundation)
260 points by lelf 7 hours ago | hide | 93 comments
6. AlphaFold2 dominates CASP14 protein structure challenge (predictioncenter.org)
169 points by momeara 6 hours ago | hide | 28 comments
7. The Gernsback Continuum by William Gibson (1981) (archive.org)
54 points by pmoriarty 3 hours ago | hide | 26 comments
8. The Sound So Loud That It Circled the Earth Four Times (nautil.us)
19 points by singhkays 1 hour ago | hide | 4 comments
9. The new 'gold rush' for green lithium (bbc.com)
28 points by clouddrover 1 hour ago | hide | discuss
10. Apple Create ML: Creating an Image Classifier Model (developer.apple.com)
178 points by tosh 6 hours ago | hide | 44 comments
11. Guybrush Fact vs. Fiction (grumpygamer.com)
115 points by pmarin 6 hours ago | hide | 35 comments
12. YC runs Work at a Startup to help you find jobs at over 700 YC-vetted startups (workatastartup.com)
2 hours ago | hide
13. Writing Rust the Elixir Way (kutt.it)
184 points by bkolobara 7 hours ago | hide | 87 comments
14. FCC Chairman Ajit Pai will step down on January 20 (cnbc.com)
107 points by dredmorbius 2 hours ago | hide | 21 comments
15. Chess tactics explained (chesstactics.org)
461 points by kensai 13 hours ago | hide | 200 comments
16. What changes when you work outside an office? (vinko.substack.com)
25 points by koide 3 hours ago | hide | 19 comments
17. Legal Concepts for Founders (clerky.com)
137 points by sarathyweb 8 hours ago | hide | 23 comments
18. No one who got Moderna's vaccine in trial developed severe Covid-19 (sciencemag.org)
275 points by jakozaur 5 hours ago | hide | 254 comments
19. Running a full desktop environment on an Amazon Kindle (nns.ee)
3 points by slondr 33 minutes ago | hide | discuss
20. Salesforce Deal to Buy Slack Expected to Be Announced Tuesday After Market Close (nbcnewyork.com)
126 points by awb 3 hours ago | hide | 87 comments
21. Show HN: Keenforms – Form Builder with No-Code Rules Engine (keenforms.com)
22 points by padseeker 3 hours ago | hide | 7 comments
22. Five Lessons from Dave Chappelle (stratechery.com)
27 points by zwieback 4 hours ago | hide | 3 comments
23. The Father of the Emoticon Chases His Great White Whale (narratively.com)
20 points by kawera 4 hours ago | hide | 6 comments
24. BiVector.net – Geometric Algebra for CGI, Vision and Engineering (bivector.net)
111 points by fanf2 10 hours ago | hide | 12 comments
25. SymPy 1.7 (github.com/sympy)
100 points by happy-go-lucky 4 hours ago | hide | 27 comments
26. Romain Grosjean walked away from F1’s scariest crash in decades (arstechnica.com)
43 points by Ashoka_rkt 1 hour ago | hide | 15 comments
27. Python Pip 20.3 Released with new resolver (pyfound.blogspot.com)
161 points by groodt 7 hours ago | hide | 130 comments
28. IRS says its own error sent $1,200 stimulus checks to non-Americans overseas (npr.org)
191 points by brundolf 4 hours ago | hide | 147 comments
29. The Tech Monopolies Go Vertical (mule.substack.com)
238 points by DenverCode 13 hours ago | hide | 124 comments
30. Fed. system to track hosp. beds and Covid-19 patients provides questionable data (sciencemag.org)
22 points by blendo 2 hours ago | hide | 4 comments

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