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1. AlphaFold: a solution to a 50-year-old grand challenge in biology (deepmind.com)
1025 points by felixr 3 hours ago | hide | 306 comments
2. BBC Basic Editor (bbcmic.ro)
54 points by mnem 52 minutes ago | hide | 4 comments
3. A free-as-in-freedom re-implementation of Google’s Android user space (microg.org)
534 points by doener 7 hours ago | hide | 135 comments
4. E Foundation – deGoogled unGoogled smartphone OS and online services (e.foundation)
241 points by lelf 6 hours ago | hide | 86 comments
5. AlphaFold2 dominates CASP14 protein structure challenge (predictioncenter.org)
134 points by momeara 5 hours ago | hide | 19 comments
6. The Gernsback Continuum by William Gibson (1981) (archive.org)
39 points by pmoriarty 2 hours ago | hide | 21 comments
7. Guybrush Fact vs. Fiction (grumpygamer.com)
95 points by pmarin 5 hours ago | hide | 30 comments
8. Apple Create ML: Creating an Image Classifier Model (developer.apple.com)
158 points by tosh 5 hours ago | hide | 39 comments
9. What changes when you work outside an office? (vinko.substack.com)
22 points by koide 2 hours ago | hide | 2 comments
10. YC runs Work at a Startup to help you find jobs at over 700 YC-vetted startups (workatastartup.com)
2 hours ago | hide
11. Writing Rust the Elixir Way (kutt.it)
156 points by bkolobara 6 hours ago | hide | 76 comments
12. Chess tactics explained (chesstactics.org)
432 points by kensai 12 hours ago | hide | 176 comments
13. FCC Chairman Ajit Pai will step down on January 20 (cnbc.com)
53 points by dredmorbius 1 hour ago | hide | 3 comments
14. Legal Concepts for Founders (clerky.com)
132 points by sarathyweb 7 hours ago | hide | 22 comments
15. No one who got Moderna's vaccine in trial developed severe Covid-19 (sciencemag.org)
248 points by jakozaur 4 hours ago | hide | 229 comments
16. Show HN: Keenforms – Form Builder with No-Code Rules Engine (keenforms.com)
18 points by padseeker 2 hours ago | hide | 7 comments
17. The Father of the Emoticon Chases His Great White Whale (narratively.com)
19 points by kawera 3 hours ago | hide | 6 comments
18. Salesforce Deal to Buy Slack Expected to Be Announced Tuesday After Market Close (nbcnewyork.com)
113 points by awb 2 hours ago | hide | 68 comments
19. Python Pip 20.3 Released with new resolver (pyfound.blogspot.com)
147 points by groodt 6 hours ago | hide | 113 comments
20. SymPy 1.7 (github.com/sympy)
89 points by happy-go-lucky 3 hours ago | hide | 20 comments
21. IRS says its own error sent $1,200 stimulus checks to non-Americans overseas (npr.org)
183 points by brundolf 3 hours ago | hide | 140 comments
22. The new 'gold rush' for green lithium (bbc.com)
4 points by clouddrover 1 hour ago | hide | discuss
23. BiVector.net – Geometric Algebra for CGI, Vision and Engineering (bivector.net)
109 points by fanf2 9 hours ago | hide | 12 comments
24. Fed. system to track hosp. beds and Covid-19 patients provides questionable data (sciencemag.org)
15 points by blendo 1 hour ago | hide | 1 comment
25. Over Half of U.S. Young Adults Now Live with Their Parents (visualcapitalist.com)
42 points by paulpauper 1 hour ago | hide | 24 comments
26. The Tech Monopolies Go Vertical (mule.substack.com)
233 points by DenverCode 12 hours ago | hide | 121 comments
27. Culture is Priority One (2010) (stanford.edu)
26 points by wallflower 4 hours ago | hide | 12 comments
28. GNU Octave 6.1.0 (gnu.org)
192 points by freddypaulo 8 hours ago | hide | 91 comments
29. Romain Grosjean walked away from F1’s scariest crash in decades (arstechnica.com)
12 points by Ashoka_rkt 28 minutes ago | hide | 1 comment
30. Show HN: StrongMap – JavaScript Map Meets Your Hard Disk (github.com/c9fe)
13 points by graderjs 2 hours ago | hide | 7 comments

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